Psoriasis is a chronic dermatological disease associated with inflammation, directly or indirectly related to a dysfunctional host-microbiome-relationship. This pertains to the gut- as well as the skin microbiome. It has been suggested that the usual and necessary communication between the microbiome and the host’s immune system is impaired.

The body is on all its external facing surfaces hosting an ecosystem of microbes (bacteria, viruses, fungi and mites) which live inside a shared biofilm on and in the skin. This consortium is called the microbiome. From no later than birth, the relationship between the body’s external facing surfaces, their local and body-wide immune-system and the microbial community evolves and a synergistic relationship is gradually established. To the point that the body needs the microbiome in order to protect itself from threatening microbes and other substances from the environment, i.e. the body is better protected with a microbiome living on the skin and gut than it would be without it – the body and microbiome has established a symbiotic relationship. This relationship constitutes the barrier towards the outside world. The microbiome can be regarded as an organ within the organ (e.g. skin or gut). It is a hardy structure and yet also a relatively delicate structure that needs to develop and mature in concert with the body. The microbial population itself, the microbiota, must consist of a diverse range of microorganisms. If this fails the symbiosis turns into a dysbiosis, which can cause inflammation and skin disease, e.g. psoriasis.

There are many sub-types of psoriasis. Independently, Aprobaxil can help when the skin has been broken, even if it is only slightly. Aprobaxil will support the immune system in establishing the desired microbiome in the area. This will reduce the itch, reduce the inflammation and close the created wound, thereby preventing a possible infection with further scar-formation. This opening can be caused by pressure from inflammation of the deeper tissue, by scratching, by breaking of a pustule / vesicle / blister and other. (Aprobaxil is not suitable for the eyes.)

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