Why is impaired wound healing common to diabetes, spinal cord injury and multiple sclerosis?

A simple scratch on the foot in a person with diabetes or to the skin in a person with spinal cord injury (SCI) or multiple sclerosis (MS) can develop into a large wound that gradually spreads under the skin leading to osteomyelitis (bone infection) and sinus tract formation, i.e. bacteria and fungi boring tunnels into the tissue…

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How antiseptics and disinfectants make you resistant to antibiotics.

It has always been assumed that antimicrobial resistance would only develop in response to the use of antibiotics, but newer data suggest that antiseptics, disinfectants and other antibacterial approaches are even worse at creating resistance. Data namely indicate that these chemicals cause the bacteria to become tolerant or resistant not only to a specific antiseptic or disinfectant,…

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Water is preferable for wound cleaning… but – Why can hydrogen peroxide (H2O2) be useful in some cases?

It is to be recognised that some wounds have a contusion zone consisting of tissue balancing on the edge between being viable (being able to live) and unviable and therefore destined to die off sooner or later. It is preferable to get rid of the unviable tissue as early in the wound healing process as possible as…

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Why should Chlorhexidine not be used before the application of MPPT?

Chlorhexidine binds strongly to the skin and tissues. Chlorhexidine is cytotoxic to fibroblasts which are the creators of the connective tissue essential to wound healing. It is toxic to human tissue cells at the same concentrations it is toxic to bacteria. http://www.ncbi.nlm.nih.gov/pubmed/3238890 Chlorhexidine’s activity lasts at least 48 hours but substantially longer periods (4 weeks) have been…

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Can I use antiseptics when preparing the wound?

The use of antiseptics is discouraged when preparing the wound for MPPT application. We strongly advise against the use of antiseptics that are cytotoxic to human cells and that accumulate in the tissue, e.g. Chlorhexidine. About Chlorhexidine If for a specific reason it is necessary to use an antiseptic prior to MPPT, a better option would be…

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