How antiseptics and disinfectants make you resistant to antibiotics.

It has always been assumed that antimicrobial resistance would only develop in response to the use of antibiotics, but newer data suggest that antiseptics, disinfectants and other antibacterial approaches are even worse at creating resistance. Data namely indicate that these chemicals cause the bacteria to become tolerant or resistant not only to a specific antiseptic or disinfectant,…

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How should the wound be cleaned before the first MPPT application?

In general, water is the best medium for wound cleaning. It removes large parts of slough and hence undesirable microbes effectively; in particular if it is applied with the pressure that can be achieved by using a wash-bottle or a large syringe. If a large contusion zone or extensive amounts of slough are present in the wound…

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Water is preferable for wound cleaning… but – Why can hydrogen peroxide (H2O2) be useful in some cases?

It is to be recognised that some wounds have a contusion zone consisting of tissue balancing on the edge between being viable (being able to live) and unviable and therefore destined to die off sooner or later. It is preferable to get rid of the unviable tissue as early in the wound healing process as possible as…

Continue Reading Water is preferable for wound cleaning… but – Why can hydrogen peroxide (H2O2) be useful in some cases?
Why should Chlorhexidine not be used before the application of MPPT?

Chlorhexidine binds strongly to the skin and tissues. Chlorhexidine is cytotoxic to fibroblasts which are the creators of the connective tissue essential to wound healing. It is toxic to human tissue cells at the same concentrations it is toxic to bacteria. http://www.ncbi.nlm.nih.gov/pubmed/3238890 Chlorhexidine’s activity lasts at least 48 hours but substantially longer periods (4 weeks) have been…

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Can I use antiseptics when preparing the wound?

The use of antiseptics is discouraged when preparing the wound for MPPT application. We strongly advise against the use of antiseptics that are cytotoxic to human cells and that accumulate in the tissue, e.g. Chlorhexidine. About Chlorhexidine If for a specific reason it is necessary to use an antiseptic prior to MPPT, a better option would be…

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Does MPPT work on an infected and/or a necrotic wound?

Yes. Procedure: If the wound contains infection and/or necrosis, remove as much pus and slough as possible using water and a moist swab. If the use of an antiseptic is necessary, 3% hydrogen peroxide (H2O2) is preferable. The use of H2O2 is contraindicated in very deep or large wounds due to risk of gas embolism. Alternatively, use…

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