Currently, there are 278 million annual wound dressing changes in UK primary care. Most dressing changes include the use of wound cleaning solutions and dressings, which for infected wounds frequently contain chemical antimicrobials such as e.g. polyaminopropyl biguanide aka polyhexamethylene biguanide aka PHMB aka polyhexanide aka polihexanide, chlorhexidine,…
New data indicate that the global annual prevalence of pressure ulcers in SCI-persons is 32.4% (Shiferaw et al. 2020). When a pressure ulcer is severe and not treated aggressively it can lead to further disability (e.g., reduced mobility, dependence, surgical intervention, amputation, fatal infection; Krause 1998). It has…
MPPT reverses wound regression caused by the antiseptic PHMB Amicapsil was used on this wound for 4 months from late June to mid-October and had been able to remove a wound infection and advance the healing of the wound. Please refer to the case report “35 year old…
Pyoderma gangrenosum (PG) is a rare neutrophilic inflammatory condition. It is characterised by painful, rapidly expanding, violaceous, undermined ulcers. Immunosuppressants are key to management, but large chronic ulcers often result. University Hospital Birmingham, UK, evaluated MPPT in three patients with chronic inactive stable PG ulcers. The patients were…
Amicapsil was evaluated in a clinical audit at Bristol University Hospital on 9 dehisced surgical wounds and a category 4 pressure ulcer. Several of the wounds displayed more than 40% slough and signs of local infection. Amicapsil rapidly lifted the slough off and facilitated a rapid build-up of…
See publication in WOUNDS here. Objective The purpose of the study was to evaluate the wound healing effects of MPPT and to compare it to antibiotics and antiseptics. The study included a wide range of wounds and ulcers, which were severely colonised to infected. The comparators were a…
A man in his 60es with a history of venous leg ulcers, cancer, colitis and eczema had walked into a camper hook at the back of a car hurting his shin. Originally the ulcer was only quite small and had seemed uncomplicated, however after 4 months it became…
A 51-year-old gentleman had developed a venous stasis ulcer on the foot in the malleolus area. He was 6 ‘ 10” / 2.10 m tall and his work involved standing up for 10 consecutive hours daily. He would always wear compression stocking when at work. This would not…
Elderly lady (type 2 diabetic) with 5 year old diabetic foot ulcer on the heel, covering the entire heel. A wide range of approaches had been taken to facilitate healing, but without luck. The ulcer was associated with considerable pain in the leg. It had for the past…
The wound had started as a small scratch 5 months prior. Due to increasing wound size, redness and heat, the small injury centre one month later provided a course of systemic antibiotics. This did not resolve the wound and over the following 4-month-period steroid cream, gel dressings, NPWT…