Skin Microbiota – A Novel Target for Promoting Burn Wound Healing

Review article discussing
the wound microbiome and Amicapsil

Review article discussing
the wound microbiome and Amicapsil

Review article discussing
the wound microbiome and Amicapsil

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Why should Chlorhexidine not be used before the application of MPPT?

Chlorhexidine binds strongly to the skin and tissues.

Chlorhexidine is cytotoxic to fibroblasts which are the creators of the connective tissue essential to wound healing. It is toxic to human tissue cells at the same concentrations it is toxic to bacteria. http://www.ncbi.nlm.nih.gov/pubmed/3238890

Chlorhexidine’s activity lasts at least 48 hours but substantially longer periods (4 weeks) have been reported (substantivity) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834637/

Chlorhexidine causes protein accumulation in the endoplasmatic reticulum which leads to ER stress and cell death, either by apoptosis or necrosis. This has been seen in fibroblasts. http://www.ncbi.nlm.nih.gov/pubmed/19027770

MPPT is available as:

Wounds, ulcers and burns

Amicapsil for humans

Trauma and surgical wounds, pressure ulcers, venous leg ulcers, diabetic foot ulcers, burns, etc.

SertaSil for animals

Trauma and surgical wounds, abscesses, amputations, and burns in dogs, horses and other animals.

Dermatology

Aprobaxil for humans

Acne, pyoderma gangrenosum, hidradenitis suppurativa, atopic dermatitis, zits etc

Adinasil for animals

Eczema, dermatitis, lick granuloma, insect bites, autoimmune skin conditions, etc.

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