NHS England and NHS Supply Chain
Amicapsil and Amicapsil SCI are available on NHS Supply Chain in the category Medical Surgical Rehabilitation & Community, as part of the Advanced Wound Care framework. See overview in NHS Supply Chain Catalogue.
The formats available for Amicapsil and Amicapsil-SCI together with their NPC codes are listed below. The difference between Amicapsil and Amicapsil-SCI is the Instructions for Use, where the Amicapsil-SCI Instructions for Use is focused on patients with immunosuppression. This can be due to medical conditions such as spinal cord injury, diabetes, and cancer; having experienced traumatic events such as accidents or extensive surgery; and receiving immunosuppressant medication or medication interfering with immune function or wound healing. For an overview of possible interactions.
| Catalogue code (NPC) | Brands | Bottle size and number of bottles | Supplier code (MPC) | # of units |
|---|---|---|---|---|
| ELZ85128 | Amicapsil | 750mg (1 Bottle) | AM-00750-01 | 1 |
| ELZ85119 | Amicapsil | 750mg (2 Bottles) | AM-00750-02 | 2 |
| ELZ85118 | Amicapsil | 750mg (10 Bottles) | AM-00750-10 | 10 |
| ELZ85124 | Amicapsil | 3grams (1 Bottle) | AM-03000-01 | 1 |
| ELZ85123 | Amicapsil | 3grams (2 Bottles) | AM-03000-02 | 2 |
| ELZ85120 | Amicapsil | 3grams (3 Bottles) | AM-03000-03 | 3 |
| ELZ85116 | Amicapsil | 10grams (1 Bottle) | AM-10000-01 | 1 |
| ELZ85117 | Amicapsil-SCI | 750mg (1 Bottle) | AMSCI-00750-01 | 1 |
| ELZ85127 | Amicapsil-SCI | 750mg (2 Bottles) | AMSCI-00750-02 | 2 |
| ELZ85125 | Amicapsil-SCI | 750mg (10 Bottles) | AMSCI-00750-10 | 10 |
| ELZ85122 | Amicapsil-SCI | 3grams (1 Bottle) | AMSCI-03000-01 | 1 |
| ELZ85121 | Amicapsil-SCI | 3grams (2 Bottles) | AMSCI-03000-02 | 2 |
| ELZ85129 | Amicapsil-SCI | 3grams (3 Bottles) | AMSCI-03000-03 | 3 |
| ELZ85126 | Amicapsil-SCI | 10grams (1 Bottle) | AMSCI-10000-01 | 1 |
Amicapsil and Amicapsil-SCI bottle sizes and packaging options available on NHS Supply Chain. See overview in NHS Supply Chain Catalogue.
How Amicapsil works.
Using physical forces, Amicapsil supports the immune system, including the skin immune system, in stabilising the wound microbiome and supporting tissue regeneration and healing. It disrupts the weaponry that bacteria use against the immune system and other bacteria. This enables the immune system and the bacteria living naturally on our skin to regain control over the wounded area and remove wound infection and in parallel generate new granulation tissue and new skin to close the wound.
Amicapsil is not antimicrobial. Instead, it acts by transitioning the wound microbiome from a dysbiotic state into an eubiotic state, which is a requirement for healing. For more information.
Efficacy and Safety
Amicapsil has been shown effective in removing wound infections, supporting tissue regeneration and reaching stable closure across wound types in immunocompetent and immunocompromised individuals.
Amicapsil is effective against antimicrobial resistant (AMR) infections and will not contribute to new resistance.
The efficacy and safety of Amicapsil have been confirmed in Randomised Controlled Trials (RCTs) and Real-World-Evidence (RWE) studies. See overview of studies.
Value-Based Procurement
The ability of Amicapsil to remove wound infection and initiate and support tissue regeneration affects patient mortality, length of stay in hospital and number of nurse visits in community, safety and quality of care, and resources.
Savings in community
The use of Amicapsil has been shown to result in substantial financial savings. For example, in the treatment of acute grade 3 pressure injuries – which is the most prevalent type – the savings were 86% the first year alone. See publication.
Savings in relation to hospital acquired wounds (e.g. PIs and SSIs)
Pressure injuries (PIs) are resource heavy on hospitals because they can lead to legal proceedings for life-changing or fatal outcomes, because they are a strain on hospital staff and because they easily lead to unplanned surgery and prolonged stays. Hospital acquired pressure injuries are also perceived as indicators of potential non-compliance with regulations on Clinical Risk management and constitute a challenge to the Safety and Quality of care provided by the hospital.
Surgical Site Infections (SSIs) and dehisced surgical wounds are becoming excessively challenging as the rate of antimicrobial resistant infections is exponentially increasing. Apart from causing prolonged length of stays, readmissions, repeat surgeries, and very low patient satisfaction, they single-handedly change otherwise successful, complicated surgical procedures into botched operations. Hospital acquired SSIs or PIs invariably lead to low patient satisfaction and low hospital ranking.
Amicapsil removes antimicrobial resistant infections and facilitates healing including in PIs and SSIs.
See publications – in relation to pressure ulcer Sams-Dodd et al. 2024 and Smith and Ridler 2024; and in relation to surgical site infections Ryan 2017 and Bilyayeva et al. 2017.
How to use
Once daily, the wound is thoroughly washed with tap-water and an unbroken layer (blanket cover) of Amicapsil is applied to all wound surfaces that can be reached. If desired, the wound can be covered with a woven, 100% pure cotton dressing or it can remain covered only with the Amicapsil, i.e. without a secondary dressing. The wound needs access to air as Amicapsil achieves its effects through the evaporation of minute amounts of moisture from the wound surface. If the wound is occluded, the Amicapsil will lose it effect. See explanatory videos.
Sustainability and Climate
Antimicrobials cause the release of carbon into the atmosphere from storage in soil and water and thereby strongly contribute to climate change. Calculations show that one course of antibiotics releases as much carbon into the atmosphere as a standard petrol car driving around the Earth 1.47 times. See publication.
Amicapsil is not antimicrobial and its ingredients are readily biologically recyclable. Furthermore, no chemicals or plastics are used in the treatment process, and all packaging is recyclable. More information.
Training and Guidance
Amicapsil is easy to use and suitable for self-care. However, a wound being treated with Amicapsil will look different compared to wounds treated with standard care approaches, and troubleshooting can require some experience in the use of Amicapsil.
We therefore recommend that we first assist you with the treatment of a relatively uncomplicated wound, in order to familiarise you with the characteristics of an Amicapsil-treated wound. Subsequently, if you experience problems with a complicated wound, we are happy to help troubleshooting. We have considerable experience in guiding HCPs. Please contact us to discuss further.
Wounds, ulcers and burns
Amicapsil for humans
Trauma and surgical wounds, pressure ulcers, venous leg ulcers, diabetic foot ulcers, burns, etc.
SertaSil for animals
Trauma and surgical wounds, abscesses, amputations, and burns in dogs, horses and other animals.
Dermatology
Aprobaxil for humans
Acne, pyoderma gangrenosum, hidradenitis suppurativa, atopic dermatitis, zits etc
Adinasil for animals
Eczema, dermatitis, lick granuloma, insect bites, autoimmune skin conditions, etc.