Ventilators cause pressure ulcers
Ventilators cause pressure ulcers
Ventilators cause pressure ulcers
NH ( patient)
NH ( patient)
NH ( patient)
Only natural ingredients
Only natural ingredients
Only natural ingredients
US FDA 2016
US FDA 2016
US FDA 2016
In connection with publication on MPPT, the
In connection with publication on MPPT, the
In connection with publication on MPPT, the
VH (patient)
VH (patient)
VH (patient)
Next-generation wound anti-infective
Amicapsil (Acapsil) for humans
Surgical wounds, diabetic foot ulcers, venous leg ulcers, pressure ulcers, trauma wounds, burns, etc.
SertaSil for animals
Surgical wounds, bite wounds, puncture wounds, abrasions, lacerations, avulsions/degloving wounds, pressure sores, burns, etc.
Aprobaxil for humans
Acne, hidradenitis suppurativa, atopic dermatitis, psoriasis, pyoderma gangrenosum, boils, furuncles, carbuncles, abscesses, zits etc.
Adinasil for animals
Eczema, dermatitis, granuloma, insect bites, autoimmune skin conditions and others
What is MPPT - micropore particle technology?
- CE-marked technology for treating wounds and dermatological conditions.
- MPPT is an anti-infective passive immunotherapy that acts via the skin microbiome. It removes the toxins and enzymes that bacteria and fungi release to inhibit immune cells and it disrupts the structure of biofilm. By disrupting the weaponry of bacteria and fungi, the immune cells regain their function and become able to control the wound environment. It involves no antimicrobial components.
- MPPT removes wound infections 60% quicker compared to antibiotics and antiseptics. It is effective on wide range of wound types and in immuno-normal, immunocompromised, e.g. diabetic foot ulcers, and immune deficient individuals, e.g. pressure ulcers in SCI-persons.
- MPPT is non-toxic and has not been associated with any side-effects, e.g. irritation, allergy, or bleeding. It can be used directly on muscle, tendon and bone.
- MPPT removes antibiotic resistant wound infections, e.g. Pseudomonas aeruginosa, Klebsiella pneumoniae and Serratia marcescens, and will not cause resistance.
- Easy to use, also for patient and their families. The wound or the skin area is washed with water, dried, MPPT is applied and covered with either gauze dressing or no dressing. Access of air to wound is used to ensure a healthy microbiome and to suppress infective organisms.
- World Anti-Doping Agency (WADA) in Canada has concluded that its use in wound care is permitted in sports, i.e. no doping issues.
- Hypoallergenic and has not caused wound irritation, bleeding, allergy or any other adverse events. Can be used directly on muscle, tendon and bone.
- Only contains natural non-toxic ingredients and is packed in recyclable materials. Unlike antimicrobials, MPPT has no effects on biodiversity or aquatic environment.
- Suitable for all wound types from small blisters to large trauma wounds, ulcers and burns and on infected and non-infected wounds. Can be combined with systemic antibiotic treatment for other conditions.
- Suitable for dermatological conditions and lesions, e.g. acne and hidradenitis suppurativa.
- Estimates indicate savings of 70% in secondary care and over 80% in primary care.
Publications:
Clinical case reports on file.
Evidence
Randomised comparative clinical trial with 266 patients
Amicapsil was compared to antibiotic and antiseptic. Amicapsil reduced time for removing infection and starting healing by 60% and number of hospitalisation days by 31% relative to these two major product groups. These effects were seen for general wounds, diabetic foot ulcers and venous leg ulcers.
Clinical evaluation at Bristol University Hospital
10 patients with dehisced surgical wounds. All wounds proceeded towards healing after 3 to 5 days with Amicapsil and all closed. Standard of care would have been 1 week with UrgoClean plus 2 weeks with TNP (pump) to reach a similar stage where the wound could proceed towards healing – assuming no complications.
Clinical evaluation of MPPT in wounds and pressure ulcers in spinal cord injured persons
Prospective study of MPPT including 35 wounds and pressure ulcers. It found that, even on top of osteomyelitis, MPPT removes soft tissue infection and induces tissue regeneration in all wounds. If treatment was initiated before the wound was 2 months old, the wound closed with no further complications. However, almost all wounds 6 months or older were associated with extensive abscess formation caused by K. pneumoniae or S. marcescens and these required time to remove. If osteomyelitis was present, stable exit-tracts would form to allow infectious debris to escape. MPPT is a cost-effective solution as most of the acute wounds only required 1-2 bottle of MPPT (or less). For comparison, Guest et al. (2018) found that the average cost of treating an infected pressure ulcer were £11,000 the first year only. And only 14% of these pressure ulcers closed within the first year.
Clinical evaluation of MPPT in pyoderma gangrenosum
University Hospital Birmingham, UK, evaluated MPPT in three patients with chronic inactive stable PG ulcers.
Community care and out-patients case-reports
Amicapsil has been able to initiate the healing of several non-healing wounds and ulcers, which had not responded to a wide range of approaches.
Preclinical study in wound healing model
This in vivo study had the same outcome as the clinical study.
Series of case stories from the veterinary world.
MPPT can be used for
♦ Closure of wounds that cannot be sutured
♦ Preparing an area for surgery by removing soft-tissue infection in the area
♦ Removing reminants of a diffuse tissue infection and supporting wound healing following surgery.
♦ Preventing infection in a surgical wound
♦ Inflammatory conditions with disruption of epithelial barriers in the skin
MPPT - only product on the market that in itself has been approved as a "treatment for wounds".
All other technologies used in the treatment of wounds have been approved as "tools or aids to be used in wound care", e.g. for the absorption of wound exudate and it is then assumed that this will have a positive impact on the wound healing process. The permission to claim MPPT to be a treatment with a therapeutic effect separates it from dressings, creames etc. and places it in a category comparable to pharmaceuticals. This permission was given based on the strong clinical data package and safety profile.
Storage
MPPT is temperature sensitive and needs to be stored refrigerated.
”It’s not too much of an exaggeration to say Amicapsil changed my life. From 4 weeks of absolute hell, in pain 24 hours a day, struggling at work and looking at possibly taking time off – to being pain-free, getting a full night’s sleep and back to normal at work.” NH