MPPT – Frontiers in Medicine
New MPPT clinical study:
100% closure rate of pressure ulcers

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Atopic dermatitis – and eczema (AD)

Atopic dermatitis

Atopic dermatitis, of which eczema is the most common type, is a chronic inflammatory disease of the skin characterized by very intense itching. It involves immunologic responses, inflammation and structural abnormalities in the skin resulting in a cracked skin barrier to the outside world

Eczema is the most common type of dermatitis. Eczema first appears as an episode of itching and redness of the skin. There may also be tiny bumps blisters or vesicles and the skin will usually be swollen. The severe itching leads to rubbing and scratching of the skin which will make the blisters break. The skin is now broken and exposing tiny wounds which are open for microbe invasion and infection. This is often described as “superinfection” and means that the infection is a secondary effect of the original dermatitis.

Infection is one of the main causes of scarring and it is therefore important to prevent an infection or remove it as quickly as possible. This can be achieved by using Aprobaxil straight away. It has been observed that Aprobaxil in this situation often reduces the tendency to scratch. This indicates that it can contribute to reducing the speed of spreading of the condition to the surrounding skin.

The result of severe itching which leads to rubbing and scratching is that the skin over time becomes thickened and leathery, also called lichenified. At this stage, the eczema has become chronic and is now less associated with breakage of the epidermal barrier (skin surface)and Aprobaxil can only help if there is a superinfection or the scratching creates tiny wounds.

Other types of Atopic Dermatitis create wounds which easily become infected. These are painful, can exude quite heavily, be smelly and be in very uncomfortable places – all issues that can have a serious impact on a person’s social life. These wounds can usually be very successfully treated with Aprobaxil.

Atopic dermatitis and Staph aureus

Atopic Dermatitis is associated with Staphylococcus aureus infection. A clinical study showed that Aprobaxil can remove Staph. Aureus infection and close the wound.

Skin lesions in atopic dermatitis have sodium (salt) concentrations 30-fold higher than the patient’s unlesioned skin and skin from healthy controls.

This could explain why people with atopic dermatitis often have an overgrowth of Staphylococcus aureus, a salt-loving microbe, on their skin.

It has been shown that Staph Aureus, when it becomes too dominating, can excrete toxins that change the behaviour of the body’s immune cells and turn them against the host’s own white blood cells.

The microbiome is altered in places where flares of AD are most at risk of appearing. Aprobaxil removes infections by helping the immune system balance the microbiome.

An interesting observation is that atopic dermatitis and psoriasis are both autoimmune chronic inflammatory skin conditions but the elevated salt level in the lesions in patients with atopic dermatitis is not seen in patients with psoriasis. The salt is therefore not likely to be the reason for inflammation in atopic dermatitis. Atopic dermatitis and psoriasis are associated with different types T helper cells.