A surgical wound has typically been closed by approximation of the wound edges by either suturing or other closing methods such as stapling. This is called first intention healing. A wound dehiscence means that the wound breaks in the line of the sutures or other closing method and this is usually caused by an infection.
Sometimes a dehiscence can be re-sutured but if the infection is not eradicated before that, it is most likely to open (dehisce) again. Also, an infection leaves the wound edges weak, and the sutures, or other closing method, will not have a good hold but are likely to “slide”. Usually, there is not enough skin along the edges to try suturing for a third time.
A surgical wound that has dehisced / sprung open is usually left to heal by its own means, filling up with new granulation tissue from the bottom. This is called second intention healing or closure by second intend. This process also requires that the infection is cleared.
Acapsil swiftly removes the infection without the use of antibiotics or antiseptics and this leads to faster tissue regeneration and healing / granulation and epithelialisation.
Scar formation is closely associated with infection. Therefore, the sooner an infection can be controlled the less scarring will occur.
Septicaemia / septicemia / blood poisoning means that the bacteria or other infecting agent, e.g. virus or fungus, have passed over into the blood stream and are being carried round in the body by the blood. This can cause infection in vital organs leading to organ failure, even multiple organ failure. When this happens the person experiences sepsis or septic shock which has a high probability of being fatal.
People who have just had surgery or who have wounds or injuries as a result of an accident are among those most at risk for septicaemia and sepsis.
In the UK 46,000 people die from sepsis annually. (source NHS) i.e. one person every 12 minutes.
In the US, the annual number of deaths caused by sepsis is 270,000 (source CDC), i.e. one person every 2 minutes.
A wound infection is therefore a serious risk factor and its swift removal is as matter of urgency and priority.
Acapsil removes wound infections 60% quicker than antibiotics and antiseptics.
In the US alone, at least 2 million people get an antibiotic-resistant antibiotic resistant infection and at least 23,000 people die each year. These numbers are from 2013 (source CDC).
Acapsil removes antimicrobial resistant wound infections, such as MRSA. Furthermore, Acapsil will not contribute to antimicrobial resistance / AMR.
In a clinical study, Acapsil removed the infection from surgical wounds in less than half the time (60%) compared to an antibiotic and an antiseptic. It also cut the number of days the patient needed to remain in hospital by over one third (41%).
A clinical audit, covering 9 acute dehisced surgical wounds and 1 category 4 pressure ulcer was performed at Bristol University Hospital (UK). Acapsil induced a clean healing wound in 3-5 days. All wounds reached closure. Standard-of-care at the hospital was 1 week with UrgoClean followed by 2 or more weeks with NPWT to reach the same state of healing as was achieved by 3-5 days with Acapsil.
Acapsil produced savings of 69.5%. These health economics calculations are based on the time and direct costs associated with reaching a healing wound state with Acapsil compared to 1 week with UrgoClean and 2 weeks with NPWT (the pump).